James C. Errey: search on Z-Library

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1

Crystal structure of the GLP-1 receptor bound to a peptide agonist

Jazayeri, Ali, Rappas, Mathieu, Brown, Alastair J. H., Kean, James, Errey, James C., Robertson, Nathan J., Fiez-Vandal, Cédric, Andrews, Stephen P., Congreve, Miles, Bortolato, Andrea, Mason, Jonathan

Journal:

Year:

2017

Language:

english

File:

PDF, 6.41 MB

english, 2017

2

Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine

Andrew S. Doré, Nathan Robertson, James C. Errey, Irene Ng, Kaspar Hollenstein, Ben Tehan, Edward Hurrell, Kirstie Bennett, Miles Congreve, Francesca Magnani, Christopher G. Tate, Malcolm Weir, Fiona

Journal:

Year:

2011

Language:

english

File:

PDF, 1.31 MB

english, 2011

3

Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu 5 Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile)

Christopher, John A., Aves, Sarah J., Bennett, Kirstie A., Doré, Andrew S., Errey, James C., Jazayeri, Ali, Marshall, Fiona H., Okrasa, Krzysztof, Serrano-Vega, Maria J., Tehan, Benjamin G., Wiggin, G

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.38 MB

english, 2015

4

From Disulfide- to Thioether-Linked Glycoproteins

Gonçalo J. L. Bernardes, Elizabeth J. Grayson, Sam Thompson, Justin M. Chalker, James C. Errey, Farid El Oualid, Timothy D. W. Claridge, Benjamin G. Davis

Journal:

Angewandte Chemie

Year:

2008

Language:

english

File:

PDF, 422 KB

english, 2008

5

Mechanistic Insight into Enzymatic Glycosyl Transfer with Retention of Configuration through Analysis of Glycomimetic Inhibitors

James C. Errey, Seung Seo Lee, Robert P. Gibson, Carlos Martinez Fleites, Conor S. Barry, Pierre M. J. Jung, Anthony C. O'Sullivan, Benjamin G. Davis, Gideon J. Davies

Journal:

Angewandte Chemie

Year:

2010

Language:

english

File:

PDF, 536 KB

english, 2010

6

From Disulfide- to Thioether-Linked Glycoproteins

Gonçalo J. L. Bernardes, Elizabeth J. Grayson, Sam Thompson, Justin M. Chalker, James C. Errey, Farid El Oualid, Timothy D. W. Claridge, Benjamin G. Davis

Journal:

Angewandte Chemie International Edition

Year:

2008

Language:

english

File:

PDF, 422 KB

english, 2008

7

Mechanistic Insight into Enzymatic Glycosyl Transfer with Retention of Configuration through Analysis of Glycomimetic Inhibitors

James C. Errey, Seung Seo Lee, Robert P. Gibson, Carlos Martinez Fleites, Conor S. Barry, Pierre M. J. Jung, Anthony C. O'Sullivan, Benjamin G. Davis, Gideon J. Davies

Journal:

Angewandte Chemie International Edition

Year:

2010

Language:

english

File:

PDF, 536 KB

english, 2010

8

Glycomimetic Inhibitors of Mycobacterial Glycosyltransferases: Targeting the TB Cell Wall

Ricardo Lucas, Patricia Balbuena, James C. Errey, Marie A. Squire, Sudagar S. Gurcha, Michael McNeil, Gurdyal S. Besra, Benjamin G. Davis

Journal:

Year:

2008

Language:

english

File:

PDF, 301 KB

english, 2008

9

Biacore analysis with stabilized G-protein-coupled receptors

Rebecca L. Rich, James Errey, Fiona Marshall, David G. Myszka

Journal:

Analytical Biochemistry

Year:

2011

Language:

english

File:

PDF, 1.11 MB

english, 2011

10

Group epitope mapping considering relaxation of the ligand (GEM-CRL): Including longitudinal relaxation rates in the analysis of saturation transfer difference (STD) experiments

Sebastian Kemper, Mitul K. Patel, James C. Errey, Benjamin G. Davis, Jonathan A. Jones, Timothy D.W. Claridge

Journal:

Journal of Magnetic Resonance

Year:

2010

Language:

english

File:

PDF, 734 KB

english, 2010

11

Mechanistic evidence for a front-side, SNi-type reaction in a retaining glycosyltransferase

Lee, Seung Seo, Hong, Sung You, Errey, James C, Izumi, Atsushi, Davies, Gideon J, Davis, Benjamin G

Journal:

Nature Chemical Biology

Year:

2011

Language:

english

File:

PDF, 696 KB

english, 2011

12

Atomic-Scale Detection of Organic Molecules Coupled to Single-Walled Carbon Nanotubes

Hong, Sung You, Tobias, Gerard, Ballesteros, Belén, El Oualid, Farid, Errey, James C., Doores, Katie J., Kirkland, Angus I., Nellist, Peter D., Green, Malcolm L. H., Davis, Benjamin G.

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 728 KB

english, 2007

13

Facile Conversion of Cysteine and Alkyl Cysteines to Dehydroalanine on Protein Surfaces: Versatile and Switchable Access to Functionalized Proteins

Bernardes, Gonçalo J. L., Chalker, Justin M., Errey, James C., Davis, Benjamin G.

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 662 KB

english, 2008

14

Fragment Screening of GPCRs Using Biophysical Methods: Identification of Ligands of the Adenosine A 2A Receptor with Novel Biological Activity

Chen, Dan, Errey, James C., Heitman, Laura H., Marshall, Fiona H., IJzerman, Adriaan P., Siegal, Gregg

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 1.30 MB

english, 2012

15

RmlC, a C3′ and C5′ Carbohydrate Epimerase, Appears to Operate via an Intermediate with an Unusual Twist Boat Conformation

Changjiang Dong, Louise L. Major, Velupillai Srikannathasan, James C. Errey, Marie-France Giraud, Joseph S. Lam, Michael Graninger, Paul Messner, Michael R. McNeil, Robert A. Field, Chris Whitfield, J

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.44 MB

english, 2007

16

The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery

Nathan Robertson, Ali Jazayeri, James Errey, Asma Baig, Edward Hurrell, Andrei Zhukov, Christopher J. Langmead, Malcolm Weir, Fiona H. Marshall

Journal:

Neuropharmacology

Year:

2011

Language:

english

File:

PDF, 646 KB

english, 2011

17

Probing the Breadth of Macrolide Glycosyltransferases: In Vitro Remodeling of a Polyketide Antibiotic Creates Active Bacterial Uptake and Enhances Potency

Yang, Min, Proctor, Mark R., Bolam, David N., Errey, James C., Field, Robert A., Gilbert, Harry J., Davis, Benjamin G.

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 65 KB

english, 2005

18

Flexible enzymatic and chemo-enzymatic approaches to a broad range of uridine-diphospho-sugars

Errey, James C., Mukhopadhyay, Balaram, Kartha, K. P. Ravindranathan, Field, Robert A.

Journal:

Chemical Communications

Year:

2004

Language:

english

File:

PDF, 241 KB

english, 2004

19

Identification of Novel Adenosine A 2A Receptor Antagonists by Virtual Screening

Langmead, Christopher J., Andrews, Stephen P., Congreve, Miles, Errey, James C., Hurrell, Edward, Marshall, Fiona H., Mason, Jonathan S., Richardson, Christine M., Robertson, Nathan, Zhukov, Andrei, W

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 277 KB

english, 2012

20

Biophysical Mapping of the Adenosine A 2A Receptor

Zhukov, Andrei, Andrews, Stephen P., Errey, James C., Robertson, Nathan, Tehan, Benjamin, Mason, Jonathan S., Marshall, Fiona H., Weir, Malcolm, Congreve, Miles

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.14 MB

english, 2011

21

Sugar nucleotide recognition by Klebsiella pneumoniae UDP-d-galactopyranose mutase: Fluorinated substrates, kinetics and equilibria

Errey, James C., Mann, Maretta C., Fairhurst, Shirley A., Hill, Lionel, McNeil, Michael R., Naismith, James H., Percy, Jonathan M., Whitfield, Chris, Field, Robert A.

Journal:

Organic & Biomolecular Chemistry

Year:

2009

Language:

english

File:

PDF, 177 KB

english, 2009

22

Expression and initial characterization of WbbI, a putative d-Galf:?-d-Glc ?-1,6-galactofuranosyltransferase from Escherichia coli K-12

Wing, Corin, Errey, James C., Mukhopadhyay, Balaram, Blanchard, John S., Field, Robert A.

Journal:

Organic & Biomolecular Chemistry

Year:

2006

Language:

english

File:

PDF, 181 KB

english, 2006

23

Biophysical Fragment Screening of the β 1 -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design

Christopher, John A., Brown, Jason, Doré, Andrew S., Errey, James C., Koglin, Markus, Marshall, Fiona H., Myszka, David G., Rich, Rebecca L., Tate, Christopher G., Tehan, Benjamin, Warne, Tony, Congre

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 4.13 MB

english, 2013

24

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain

Doré, Andrew S., Okrasa, Krzysztof, Patel, Jayesh C., Serrano-Vega, Maria, Bennett, Kirstie, Cooke, Robert M., Errey, James C., Jazayeri, Ali, Khan, Samir, Tehan, Ben, Weir, Malcolm, Wiggin, Giselle R

Journal:

Year:

2014

Language:

english

File:

PDF, 4.93 MB

english, 2014

25

Functional Annotation and Kinetic Characterization of PhnO from Salmonella enterica †

Errey, James C., Blanchard, John S.

Journal:

Year:

2006

Language:

english

File:

PDF, 106 KB

english, 2006

26

Site-selective chemoenzymatic construction of synthetic glycoproteins using endoglycosidases

Fernández-González, Marta, Boutureira, Omar, Bernardes, Gonçalo J. L., Chalker, Justin M., Young, Matthew A., Errey, James C., Davis, Benjamin G.

Journal:

Chemical Science

Year:

2010

Language:

english

File:

PDF, 324 KB

english, 2010

27

Characterisation of Streptomyces spheroides NovW and revision of its functional assignment to a dTDP-6-deoxy-d-xylo-4-hexulose 3-epimerase

Tello, Mónica, Jakimowicz, Piotr, Errey, James C., Freel Meyers, Caren L., Walsh, Christopher T., Buttner, Mark J., Lawson, David M., Field, Robert A.

Journal:

Chemical Communications

Year:

2006

Language:

english

File:

PDF, 395 KB

english, 2006

28

Saturation transfer difference NMR reveals functionally essential kinetic differences for a sugar-binding repressor protein

Pérez-Victoria, Ignacio, Kemper, Sebastian, Patel, Mitul K., Edwards, John M., Errey, James C., Primavesi, Lucia F., Paul, Matthew J., Claridge, Timothy D. W., Davis, Benjamin G.

Journal:

Chemical Communications

Year:

2009

Language:

english

File:

PDF, 1.04 MB

english, 2009

29

Dissecting the reaction of Phase II metabolites of ibuprofen and other NSAIDS with human plasma protein

Monrad, Rune Nygaard, Errey, James C., Barry, Conor S., Iqbal, Mazhar, Meng, Xiaoli, Iddon, Lisa, Perrie, Jennifer A., Harding, John R., Wilson, Ian D., Stachulski, Andrew V., Davis, Benjamin G.

Journal:

Chemical Science

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

30

Discovery of HTL6641, a dual orexin receptor antagonist with differentiated pharmacodynamic properties

Christopher, John A., Aves, Sarah J., Brown, Jason, Errey, James C., Klair, Suki S., Langmead, Christopher J., Mace, Oliver J., Mould, Richard, Patel, Jayesh C., Tehan, Benjamin G., Zhukov, Andrei, Ma

Journal:

Year:

2015

Language:

english

File:

PDF, 1.13 MB

english, 2015

31

Preparation of purified GPCRs for structural studies

Cooke, Robert M., Koglin, Markus, Errey, James C., Marshall, Fiona H.

Journal:

Biochemical Society Transactions

Year:

2013

Language:

english

File:

PDF, 320 KB

english, 2013

32

Biosensor-based affinities and binding kinetics of small molecule antagonists to the adenosine A2A receptor reconstituted in HDL like particles

Segala, Elena, Errey, James C., Fiez-Vandal, Cédric, Zhukov, Andrei, Cooke, Robert M.

Journal:

Year:

2015

Language:

english

File:

PDF, 843 KB

english, 2015

33

Extra-helical binding site of a glucagon receptor antagonist

Jazayeri, Ali, Doré, Andrew S., Lamb, Daniel, Krishnamurthy, Harini, Southall, Stacey M., Baig, Asma H., Bortolato, Andrea, Koglin, Markus, Robertson, Nathan J., Errey, James C., Andrews, Stephen P.,

Journal:

Year:

2016

Language:

english

File:

PDF, 6.28 MB

english, 2016

34

Controlling the dissociation of ligands from the Adenosine A2A receptor through modulation of salt bridge strength.

Segala, Elena, Guo, Dong, Cheng, Robert K Y, Bortolato, Andrea, Deflorian, Francesca, Dore, Andrew S, Errey, James C., Heitman, Laura H., IJzerman, Adriaan P., Marshall, Fiona H., Cooke, Robert M

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

35

Amino alditols as inhibitors of mycobacterial cell wall biosynthesis

Errey, James C., Newbury, Giles D., Ballell, Lluis, Field, Robert A.

Journal:

Biochemical Society Transactions

Year:

2002

Language:

english

File:

PDF, 94 KB

english, 2002

36

Intracellular allosteric antagonism of the CCR9 receptor

Oswald, Christine, Rappas, Mathieu, Kean, James, Doré, Andrew S., Errey, James C., Bennett, Kirstie, Deflorian, Francesca, Christopher, John A., Jazayeri, Ali, Mason, Jonathan S., Congreve, Miles, Coo

Journal:

Year:

2016

Language:

english

File:

PDF, 8.00 MB

english, 2016

37

Structural elucidation of ligand binding sites in family B GPCRs and their application in drug discovery

Jazayeri, Ali, Doré, Andrew, Lamb, Daniel, Krishnamurthy, Harini, Southall, Stacey, Baig, Asma, Bortolato, Andrea, Koglin, Markus, Robertson, Nathan, Errey, James, Andrews, Stephen, Brown, Alastair, C

Journal:

Acta Crystallographica Section A Foundations and Advances

Year:

2016

Language:

english

File:

PDF, 57 KB

english, 2016

38

Corrigendum: Crystal structure of the GLP-1 receptor bound to a peptide agonist

Jazayeri, Ali, Rappas, Mathieu, Brown, Alastair J. H., Kean, James, Errey, James C., Robertson, Nathan J., Fiez-Vandal, Cédric, Andrews, Stephen P., Congreve, Miles, Bortolato, Andrea, Mason, Jonathan

Journal:

Year:

2017

Language:

english

File:

PDF, 45 KB

english, 2017

39

Structures of Human A 1 and A 2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity

Cheng, Robert K.Y., Segala, Elena, Robertson, Nathan, Deflorian, Francesca, Doré, Andrew S., Errey, James C., Fiez-Vandal, Cédric, Marshall, Fiona H., Cooke, Robert M.

Journal:

Year:

2017

Language:

english

File:

PDF, 3.92 MB

english, 2017

40

Precise Probing of Residue Roles by Post-Translational β,γ-C,N Aza-Michael Mutagenesis in Enzyme Active Sites

Dadová, Jitka, Wu, Kuan-Jung, Isenegger, Patrick G., Errey, James C., Bernardes, Gonçalo J. L., Chalker, Justin M., Raich, Lluís, Rovira, Carme, Davis, Benjamin G.

Journal:

ACS Central Science

Year:

2017

Language:

english

File:

PDF, 3.48 MB

english, 2017

41

Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals

Rucktooa, Prakash, Cheng, Robert K. Y., Segala, Elena, Geng, Tian, Errey, James C., Brown, Giles A., Cooke, Robert M., Marshall, Fiona H., Doré, Andrew S.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.66 MB

english, 2018

42

Structure Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu 5 ) X-ray structures

Christopher, John, Orgován, Zoltán, Congreve, Miles, Dore, Andrew S, Errey, James C., Marshall, Fiona H., Mason, Jonathan S., Okrasa, Krzysztof, Rucktooa, Prakash, Serrano-Vega, Maria J., Ferenczy, Gy

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.27 MB

english, 2018

43

Comparison of orexin 1 and orexin 2 ligand binding modes using X-ray crystallography and computational analysis

Rappas, Mathieu, Ali, Ammar, Bennett, Kirstie A, Brown, Jason D, Bucknell, Sarah J, Congreve, Miles, Cooke, Robert M, Cseke, Gabriella, de Graaf, Chris, Dore, Andrew S, Errey, James C, Jazayeri, Ali,

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 3.39 MB

english, 2019

44

Comparison of orexin 1 and orexin 2 ligand binding modes using X-ray crystallography and computational analysis

Rappas, Mathieu, Ali, Ammar, Bennett, Kirstie A, Brown, Jason D, Bucknell, Sarah J, Congreve, Miles, Cooke, Robert M, Cseke, Gabriella, de Graaf, Chris, Dore, Andrew S, Errey, James C, Jazayeri, Ali,

Journal:

Journal of Medicinal Chemistry

Year:

2019

File:

PDF, 3.39 MB

2019

45

Production of membrane proteins in industry: The example of GPCRs

Errey, James C., Fiez-Vandal, Cédric

Journal:

Protein Expression and Purification

Year:

2020

Language:

english

File:

PDF, 1.18 MB

english, 2020

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